Healthcare Private Equity 2025: Mega-Deals, Mid-Market Momentum, and Global Shifts

Healthcare Private Equity 2025: Mega-Deals, Mid-Market Momentum, and Global Shifts

Aug 26, 2025 Private Equity Healthcare Providers and Services

Healthcare Private Equity 2025: Mega-Deals, Mid-Market Momentum, and Global Shifts

Overview

Healthcare private equity (PE) rebounded in 2024 with deal volume reaching an impressive $115 billion—the second-highest annual total on record. This surge is powered by megadeals in biopharma, carve-outs, and renewed investor interest across North America and Europe, while Asia-Pacific activity lags behind. As we move into 2025, emerging strategies and mid-market dynamism are poised to redefine the landscape.


1. 2024’s PE Surge: Scale, Resilience, and Strategic Moves

  • Global volume hit $115B, fueled by multiple megadeals that exceeded $5B—up from just two in 2023 and one in 2022.


  • Regional heatmap:

    • North America led at 65%, followed by Europe at 22%, and Asia-Pacific lagging at 12%.

    • Biopharma and healthcare IT sectors were primary deal generators.
       


2. Mid-Market PE Funds Outperforming—Aggressively

  • Mid-market healthcare funds (with $500M–$4B AUM) have surged ahead, clocking 40% higher fundraising than in previous three-year cycles.
     

  • These funds are pivoting beyond traditional provider acquisitions, expanding strongly into healthcare IT, services, biopharma, and medtech.


3. Asia-Pacific Lags, But Opportunities Are Rising

  • Deal activity in Asia-Pacific dropped by 49%, as North America and Europe absorbed the global momentum.


  • That said, investor interest in emerging markets like India, Japan, and South Korea continues to grow.
     


4. The Power of Carve-Outs and Exit Optimization

  • Healthcare PE firms are increasingly targeting carve-outs as a strategic avenue to deploy capital, especially given limited LP liquidity.

  • Sellers, too, are under pressure—both corporate and PE-owned targets must articulate clear value-creation stories to attract investment.



Strategic Takeaways for 2025

Focus Area

Why It Matters

Lean, mid-market plays

High returns and agility, suited to volatility and opportunity

Embrace carve-outs

Unlock value from underperforming or divested units

Regional diversification

Opportunity beyond North America remains untapped

Strengthen business case

Sectors must show tangible value creation to attract buyers


Final Thought

2024 marked a turning point—private equity re-entered healthcare with conviction. In 2025, mid-market strategies, renewed deal models, and global breadth will govern which investors capture long-term value.

Would you like a tailored companion blog, perhaps focused on mid-market deal dynamics, healthcare carve-outs, or Asia-Pacific opportunities?


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